- OVERVIEW -Runes
Runes, rune sourcing, and upgrade notes.
Runes are equipable passive items that boost damage, survivability, or luck.
The main rune pool comes from Rune Dungeons, while the two secret runes are tied to Infinite Tower.
Rune Dungeon drop chance scales with both difficulty and the later waves of a run, so W15 on Extreme is much better than early waves on Easy.
- DROP TABLE -What Falls
Suppression Rune
Rare D 10% Damage Reduction 16% Damage Reduction Lowest-impact defensive rune and usually replaced quickly.
10%
Guardian Rune
Epic C +39% Max Health +62.4% Max Health Solid health padding, but lower value than damage and luck runes.
39%
Frost Rune
Legendary C Freeze 2 seconds and +30% Damage Freeze 3.2 seconds and +48% Damage Freeze utility is nice, but it is not a top-end damage rune.
30%
Blood Rune
Mythical C Bleed 65% Damage over 5 seconds Bleed 97% Damage over 5 seconds Bleed is useful, but it trails the highest raw damage runes.
65%
Inferno Rune
Mythical C Burn 70% Damage over 4 seconds Burn 112% Damage over 4 seconds Burn damage is decent, but it does not keep up with the best current choices.
70%
Destruction Rune
Legendary B +25% Damage +40% Damage Strong direct damage rune and a good bridge before the best mythicals.
25%
Fortune Rune
Mythical A +10% Luck +16% Luck Best non-secret luck option for drop and crate farming builds.
10%
Wrath Rune
Mythical A +40% Damage +64% Damage Very strong raw damage rune and one of the best Rune Dungeon drops.
40%
Havoc Rune
Mythical S +55% Damage +88% Damage Best non-secret damage rune in the current wiki rankings.
55%
Radiant Rune
Secret S +17.5% Luck +28% Luck Top luck rune and one of the two current endgame chase runes from Infinite Tower, not Rune Dungeon.
17.5%